ESB-NANOSTEM Joint Sympoium
Title: New nanomaterials for neural stem cells drug delivery
Brain conditions such as neurodegenerative diseases, stroke and traumatic injuries are a major burden in modern society. Because neural stem cells (NSCs) can differentiate into new neural cells, including neurons, the regulation of their proliferation, differentiation and migration represents a promising regenerative/therapeutic strategy. The hypothesis of NANOSTEM project is that novel nanoparticles (NPs) combined with recent developed pharmaceuticals can be an efficient approach to control the biological activity of NSCs.
During this multidisciplinary symposium 14 Early-Stage Researchers will present their recent findings and advancements within the frame of the NANOSTEM European Project. The topics covered will be ranging from organic and polymer chemistry, biochemistry, molecular biology, neuroscience, and computational science, with particular emphasis on:
1) synthesis of nanomaterials and uploading of the therapeutics
2) evaluation of the permeation and efficacy of the formulations against neural stem cells
3) in vivo studies to assess the toxicity of the formulations developed and their ability to tackle the brain.
NANOSTEM is a Marie Skłodowska-Curie Innovative Training Network (ITN) funded by the European Commission through the Horizon 2020 Research and Innovation programme (H2020-MSCA-ITN-2017 G.A. 764958). The network is coordinated by Prof Marina Resmini at QMUL and comprises 9 beneficiary teams and 3 associated partners, from 6 different European countries, both from academia and industry.